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WHAT ARE
LIFE SCIENCES &
PARTICLE ANALYSIS?

 

Medical Diagnostics and Detection

  

Brightfield and Darkfield Microscopy

 

Fluorescence, Confocal, and DIC Microscopy

 

Particle Analysis with Flow Cytometry

Applications within the medical, life sciences, and biotechnology industries often require the integration of microscopic imaging systems with analytical instruments to analyze tissue samples or cells, on incredibly small scales, for properties such as shape, size, or confluence. In addition to analytical medical devices, these optical and imaging components are also found inside particle analysis devices. One such device is a flow cytometer which uses light scattering directionality and, occasionally, multiple lasers of different wavelengths with dichroic mirrors and other filters to detect the physical and chemical properties of particles flowing through a fluidic sampling chamber. Flow cytometry is used in the life sciences industry for cell counting and sorting, but also in non-organic industries which must quantify the number of fine particles in a slurry, such as particles of titanium dioxide (TiO2) in paint.

Why Life Sciences and Particle Analysis?

Advances in optical technology help to enable new techniques for the timely detection and treatment of numerous diseases like COVID-19; all of which can reduce the rate of transmission and mortality. The early detection of other diseases like cancer, which consists of rapidly mutating abnormal cells that can divide, grow, and spread uncontrollably through the body in a short period of time, is critical to timely patient treatment and survivability.

Cancer Survivors by State

Optics for Life Sciences and Particle Analysis

Imaging systems for life sciences applications are not always visible; complex diagnostic equipment is comprised of components including microscope objectives and lenses, filters, polarizers, lasers, cameras, and more. Microscopy techniques, such as brightfield and darkfield microscopy, fluorescence, and differential interference contrast (DIC) microscopy, are used to analyze a variety of details on samples and to perform many other advanced medical or diagnostic procedures.

Edmund Optics (EO) is a world class optics and photonics manufacturer with over 78 years of experience in optics, design, testing, and manufacturing. Additionally, EO offers a broad selection of versatile and off-the-shelf products, which are continuously updated to support current, relevant challenges for life sciences and particle analysis. Learn more about Edmund Optics and our World-Class Imaging Optics and Manufacturing Capabilities.

Edmund Optics’ Solutions for Life Sciences & Particle Analysis

Edmund Optics’ Solutions for Life Sciences & Particle Analysis

Technical Information and Tools

Videos

Informative corporate or instructional videos ranging from simple tips to application-based demonstrations of product advantages.

Introduction to Advanced Diagnostics

Introduction to Advanced Diagnostics

 

Application Notes

Technical information and application examples including theoretical explanations, equations, graphical illustrations, and much more.

11 Best Practices for
Better Imaging

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6 Fundamental Parameters of an Imaging System

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From Lens to Sensor: Limitations on Collecting Information

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Imaging Electronics 101: Understanding Camera Sensors for Machine Vision Applications
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Imaging Electronics 101: Basics of Digital Camera Settings for Improved Imaging Results
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Diffraction Limit


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Fluorescence Microscopy: In-Line Illumination with Imaging Filters

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Fluorophores and Optical Filters for Fluorescence Microscopy

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Optical Cage System Application: Differential Interference Contrast (DIC) Digital Microscope
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Optical Microscopy Application: Brightfield Illumination

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Optical Microscopy Application: Darkfield Illumination

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Optical Microscopy Application: Differential Interference Contrast

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Optical Microscopy Application: Fluorescence

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Optical Microscopy Application: Phase Contrast

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Optical Microscopy Application: Brightfield Illumination

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Understanding Infinity Corrected Objective Resolving Power and Magnification
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Understanding Microscopes and Objectives
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Technical Articles

Links to technical articles appearing in industry publications authored by Edmund Optics or featuring contributions from EO's engineering team and key management.

"Vision & Sensors Lens Selection Guide, Part 1" by Nick Sischka - Quality Vision & Sensors

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"Lens Selection Guide, Part 2" by Nick Sischka - Quality Vision & Sensors

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"Vision Systems for 3D Measurement Require Care to Ensure Alignment" by Jessica Gehlhar - Industrial Photonics
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"Miniaturization, Increased Resolution Drive Microscopy’s Future" by Nirantha Balagopal - BioPhotonics
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"How To Maximise The Performance Of An Imaging System" by Daniel Adams - Assemblaggio & Meccatronica

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"Portable Microscopy/Optics Innovations: High-performance, low-profile microscopy" by Stephan Briggs and Cory Boone - BioOptics World
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"Get the Picture! Easily incorporate microscopic imaging into small-scale applications" by Stephan Briggs - Optik & Photonik

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"MICROSCOPY: Off-the-shelf components enable a new generation of confocal microscopy" by Matthew S. Muller and Stephan Briggs - Laser Focus World
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"Vision Helps Reshape Microscopy, Biomedical Imaging Convergence" by Winn Hardin - Machine Vision Online
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"Advantages of High OD Filters to Microscopy" by Paul Gelsinger-Austin - Spectroscopy

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Working on Optics for a
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References

1American Cancer Society. Cancer Treatment & Survivorship Facts & Figures 2019-2021. Atlanta: American Cancer Society; 2019.

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